ATF3 Antibody

Code CSB-PA112956XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) Atf3 Polyclonal antibody
Uniprot No. Q9XZS8
Target Names Atf3
Alternative Names Atf3 antibody; A3-3 antibody; CG11405Activating transcription factor 3 antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) ATF3 protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
Transcription factor which binds to the cAMP response element (CRE)
Gene References into Functions
  1. provide a mechanism to explain how an ATF3-Raw module controls JNK signalling to maintain normal intestinal barrier function during acute infection PMID: 28272390
  2. Atf3 controls the microtubule network and plays important role in cell differentiation and cell polarity. PMID: 29494583
  3. Loss of Atf3 results in chronic inflammation and starvation responses mounted primarily by the larval gut epithelium, while the fat body suffers lipid overload, causing energy imbalance and death. PMID: 22851689
Subcellular Location Nucleus
Protein Families BZIP family, ATF subfamily
Tissue Specificity Moderate expression in some regions of the larval nervous system, the ring gland and imaginal disks. High expression in larval gut, excretory malpighian tubules, salivary glands, and, to a lesser extent, the fat body where levels are approximately 2.5-fol
Database Links

KEGG: dme:Dmel_CG11405

STRING: 7227.FBpp0303417

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