atoh7 Antibody

Code CSB-PA805214XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) atoh7 Polyclonal antibody
Uniprot No.
Target Names
atoh7
Alternative Names
atoh7 antibody; ath5 antibody; lak antibody; si:packtrz.1Protein atonal homolog 7 antibody; Helix-loop-helix protein zATH-5 antibody; zATH5 antibody; Protein atonal homolog 5 antibody; Protein lakritz antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) atoh7 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor involved in the differentiation of retinal ganglion cells. Required for retinal circadian rhythm photoentrainment.
Gene References into Functions
  1. Atoh7 indirectly impacts amacrine-cell division modes to regulate the right number of Barhl2-expressing cells. Atoh7 itself influences the subtypes of Barhl2-dependent amacrine cells. PMID: 23035102
  2. Observations suggest that Irx2 functions downstream of irx1a to control shh expression in the retina. Study proposed a novel transcriptional cascade of ath5-irx1a-irx2a in the regulation of hedgehog waves during vertebrate retinal development. PMID: 21046643
  3. Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina. PMID: 15857917
Subcellular Location
Nucleus.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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