ATXR3 Antibody

Code CSB-PA515806XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ATXR3 Polyclonal antibody
Uniprot No.
Target Names
ATXR3
Alternative Names
ATXR3 antibody; SDG2 antibody; SET2 antibody; At4g15180 antibody; dl3635w antibody; FCAALL.214Histone-lysine N-methyltransferase ATXR3 antibody; EC 2.1.1.354 antibody; Protein SET DOMAIN GROUP 2 antibody; Trithorax-related protein 3 antibody; TRX-related protein 3 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ATXR3 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase specifically required for trimethylation of 'Lys-4' of histone H3 (H3K4me3) and is crucial for both sporophyte and gametophyte development.
Gene References into Functions
  1. SDG2-mediated Histone H3 Lys 4 trimethylation is an essential epigenetic mark of the gametophyte chromatin landscape. PMID: 28455402
  2. SDG2-mediated H3K4 methylation is required for proper Arabidopsis root growth and development. PMID: 23483879
  3. The novel-class H3K4 methyltransferase, ATXR3, is a transcriptional activator that plays a role in the FLC activation and establishing the winter-annual habit. PMID: 22378382
  4. Anther and pollen development is impaired in sdg2-1 mutant plants. SDG2 activates gene transcription through H3K4 trimethylation. PMID: 21037105
  5. SDG2 is a robust and specific H3K4 methyltransferase in vitro, and the loss of SDG2 leads to a drastic decrease in H3K4me3 in vivo. PMID: 20937886

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Subcellular Location
Nucleus.
Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, TRX/MLL subfamily
Tissue Specificity
Expressed in roots, leaves, stems and inflorescences.
Database Links

KEGG: ath:AT4G15180

STRING: 3702.AT4G15180.1

UniGene: At.21894

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