ATXR7 Antibody

Code CSB-PA218201XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ATXR7 Polyclonal antibody
Uniprot No.
Target Names
ATXR7
Alternative Names
ATXR7 antibody; SDG25 antibody; At5g42400 antibody; MDH9.9 antibody; Histone-lysine N-methyltransferase ATXR7 antibody; EC 2.1.1.354 antibody; EC 2.1.1.357 antibody; Protein SET DOMAIN GROUP 25 antibody; Trithorax-related protein 7 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ATXR7 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS-box genes of the MAF family. Required for histone H3 dimethylation on 'Lys-36' H3K36me2 at the FLC locus. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. Involved in the control of seed dormancy and germination.
Gene References into Functions
  1. SDG8 and SDG25 contribute to plant immunity directly through HLM or indirectly through H2Bubn and by regulating expression of plant immunity genes, accumulation of lipids, biosynthesis of carotenoids, and maintenance of cuticle integrity. PMID: 27354553
  2. ATXR7 is required for the regulation of SNC1 and RPP4 expression, suggesting that MOS9 functions together with ATXR7 to regulate the expression of NB-LRR-encoding Resistance genes. [ATXR7] PMID: 23690534
  3. H3K4 methylases, atxr7, appear to be required for methylation of lysine 4 of histone H3 and for transcriptional activation of FLOWERING LOCUS C. PMID: 19855050
  4. Expression of FLC is down-regulated in the sdg25-1 histone methyltransferase mutant, and H3K36 dimethylation is slightly down-regulated at some regions of FLC. PMID: 19726574
Subcellular Location
Nucleus.
Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, TRX/MLL subfamily
Tissue Specificity
Expressed in the shoot and root apices, vascular tissues and mesophyll cells of rosette leaves.
Database Links

KEGG: ath:AT5G42400

STRING: 3702.AT5G42400.1

UniGene: At.30177

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