AYR1 Antibody

Code CSB-PA331175XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) AYR1 Polyclonal antibody
Uniprot No.
Target Names
AYR1
Alternative Names
AYR1 antibody; YIL124WNADPH-dependent 1-acyldihydroxyacetone phosphate reductase antibody; ADR antibody; EC 1.1.1.101 antibody; 1-acyl DHAP reductase antibody; Acyl/alkyl DHAP reductase antibody; Acylglycerone-phosphate reductase antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) AYR1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively. Required for the biosynthesis of phosphatidic acid via the DHAP pathway, where it reduces 1-acyl DHAP to lysophosphatidic acid (LPA). Also has triacylglycerol (TAG) lipase activity. Involved in the mobilization of the non-polar storage lipids triacylglycerols (TAGs) from lipid particles by hydrolysis of TAGs. Required for spore germination. Plays a role in cell wall biogenesis, but this effect may be indirect by affecting the activities of cell wall synthesis enzymes. Lipolysis of TAG by AYR1 is essential for starvation-induced autophagy. Forms an NADPH-regulated cation-selective channel in the mitochondrial outer membrane.
Gene References into Functions
  1. short-chain dehydrogenase-related protein Ayr1 forms an NADPH-regulated channel in the outer mitochondrial membrane. PMID: 28916712
  2. Ayr1p as a novel triacylglycerol lipase in Saccharomyces cerevisiae PMID: 24187129
Subcellular Location
Lipid droplet. Mitochondrion outer membrane. Endoplasmic reticulum.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Database Links

KEGG: sce:YIL124W

STRING: 4932.YIL124W

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