BDF1 Antibody

Code CSB-PA336087XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) BDF1 Polyclonal antibody
Uniprot No.
Target Names
BDF1
Alternative Names
BDF1 antibody; YLR399C antibody; L8084.18Bromodomain-containing factor 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) BDF1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor involved in the expression of a broad class of genes including snRNAs. Required for sporulation and DNA-damage repair. Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation.
Gene References into Functions
  1. Bdf1 bromodomains are required for the expression of key meiotic genes and the master regulator NDT80. PMID: 28068333
  2. Overexpression of HAL2 in bdf1Delta mutant proterin increases gene expression in the iron-acquisition pathway. PMID: 27387517
  3. This probably is the first report showing that the transcription factor Bdf1p regulates endocytosis under salt stress via LSP1, a major component of eisosomes that regulate the sites of endocytosis. PMID: 25572496
  4. Bdf1p directly regulates BDF2 transcription by binding to its promoter. PMID: 23452060
  5. The data demonstrate that, under the NaCl stress, the absence of Bdf1p leads to mitochondrial dysfunction, including decreasing of mitochondrial membrane potential and accumulation of reactive oxygen species, and chromatin fragmentation and condensation. PMID: 19220868
  6. Report interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. PMID: 19782036

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Subcellular Location
Nucleus.
Database Links

KEGG: sce:YLR399C

STRING: 4932.YLR399C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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