BicC Antibody

Code CSB-PA634498XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) BicC Polyclonal antibody
Uniprot No.
Target Names
BicC
Alternative Names
BicC antibody; CG4824Protein bicaudal C antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) BicC protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression.
Gene References into Functions
  1. Impaired BicC function induces renal cystogenesis in Drosophila.BicC is necessary for proper Malpighian tubule function. PMID: 28406902
  2. Bic-C regulates expression of specific germline mRNAs by controlling their poly(A)-tail length. PMID: 17981137
  3. Bic-C associates with a Trailer Hitch/Me31B complex and is required for efficient Grk secretion. PMID: 19389362
Protein Families
BicC family
Tissue Specificity
Abundantly expressed in ovaries and early embryos.
Database Links

KEGG: dme:Dmel_CG4824

STRING: 7227.FBpp0080361

UniGene: Dm.7521

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