HUB2 Antibody

Code CSB-PA653537XA01OFG
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Product Details

Full Product Name
Rabbit anti-Oryza sativa subsp. japonica (Rice) HUB2 Polyclonal antibody
Uniprot No.
Target Names
HUB2
Alternative Names
HUB2 antibody; BRE1B antibody; FRRP1 antibody; Os10g0565600 antibody; LOC_Os10g41590 antibody; OsJ_031219 antibody; OsJ_32496 antibody; OSJNBa0057L21E3 ubiquitin-protein ligase BRE1-like 2 antibody; EC 2.3.2.27 antibody; Flowering-related RING protein 1 antibody; Protein HISTONE MONOUBIQUITINATION 2 antibody; OsHUB2 antibody; RING-type E3 ubiquitin transferase BRE1-like 2 antibody
Raised in
Rabbit
Species Reactivity
Oryza sativa subsp. japonica (Rice)
Immunogen
Recombinant Oryza sativa subsp. japonica (Rice) HUB2 protein
Immunogen Species
Oryza sativa subsp. japonica (Rice)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is a prerequisite for H3 Lys-4 methylation (H3K4me). It thereby plays a central role in histone code and gene regulation. H2B monoubiquitination, mediated by HUB2, modulates transcriptional regulation of anther development, likely by promoting histone H3K4 dimethylation (H3K4me2) in the chromatin of the key tapetum degradation-related genes C4, CP1 and UDT1. H2B monoubiquitination, mediated by HUB2, modulates transcriptional regulation of genes associated with flowering time and plant yield.
Subcellular Location
Nucleus.
Protein Families
BRE1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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