btd Antibody

Code CSB-PA631539XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) btd Polyclonal antibody
Uniprot No.
Target Names
btd
Alternative Names
btd antibody; CG12653Transcription factor btd antibody; Protein buttonhead antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) btd protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the development of the antennal, intercalary and mandibular segments of the head.
Gene References into Functions
  1. Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead. PMID: 25285447
  2. Btd prevents the premature differentiation by suppressing the expression of Prospero in immature intermediate neural progenitor cells. Btd functions cooperatively with Pointed P1 to promote the generation of the above cells. PMID: 25285448
  3. By simultaneously removing the function of two Sp8 orthologs, buttonhead (btd) and Sp1, during Drosophila embryogenesis, we find that adult leg development is completely abolished. PMID: 20585625
  4. Results show that buttonhead and Sp1 induce the formation and are required for the growth of the ventral imaginal discs. PMID: 14561634
Subcellular Location
Nucleus.
Database Links

KEGG: dme:Dmel_CG12653

STRING: 7227.FBpp0071314

UniGene: Dm.2928

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