Btk29A Antibody

Code CSB-PA198199XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Btk29A Polyclonal antibody
Uniprot No.
Target Names
Btk29A
Alternative Names
Btk29A antibody; Src2 antibody; Src29A antibody; Tec29 antibody; CG8049Tyrosine-protein kinase Btk29A antibody; EC 2.7.10.2 antibody; Dsrc28C antibody; Dsrc29a antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Btk29A protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for proper ring canal development. Also required for the development of male genitalia and for adult survival.
Gene References into Functions
  1. Btk29A is required for the establishment of egg chamber polarity presumably through the regulation of subcellular localization of its downstream proteins, including Cno. PMID: 28639397
  2. Btk29A(ficP) mutant males null for the Btk29A type 2 isoform, a fly homolog of the nonreceptor tyrosine kinase Btk, show no courtship suppression, while Btk29A hypomorphic males exhibit a complete loss in courtship suppression within 30 min. PMID: 26782301
  3. Btk29A is required non cell-autonomously for the invagination of the spiracular chamber in Drosophila PMID: 25305143
  4. role of Btk29A type 2 on a transcriptomic level in larval CNS and adult heads PMID: 22574122
  5. Btk29A tyrosine kinase has a role in phosphorylation and enzymatic activity of phosphoglucomutase in drosophila PMID: 12729618
  6. In the absence of its PH domain, Tec29 constitutively localizes to ring canals, but still requires Src64 for full activation PMID: 14976559
  7. Tec29 regulates both the actin cytoskeleton and the cell cycle to facilitate the morphogenesis of the embryonic salivary glands. PMID: 16000381

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Subcellular Location
Note=Ring canals.
Protein Families
Protein kinase superfamily, Tyr protein kinase family, TEC subfamily
Tissue Specificity
Ring canals in the egg chambers and imaginal disks of third-instar larvae.
Database Links

KEGG: dme:Dmel_CG8049

STRING: 7227.FBpp0079237

UniGene: Dm.7306

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