BZR1 Antibody

Code CSB-PA854652XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) BZR1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
BZR1 antibody; BIS2 antibody; At1g75080 antibody; F9E10_7Protein BRASSINAZOLE-RESISTANT 1 antibody; Protein BIN2 SUBSTRATE 2 antibody
Raised in
Species Reactivity
Arabidopsis thaliana
Recombinant Arabidopsis thaliana BZR1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2).
Gene References into Functions
  1. The brassinosteroid-regulated transcription factors BZR1/BES1 function as a coordinator in multisignal-regulated plant growth. PMID: 29673687
  2. light-regulated phosphorylation change of BZR1 requires the existence of endogenous brassinosteroid as well as functional BIN2 and protein phosphatase 2A (PP2A). PMID: 28396515
  3. BZR1, a BES1 homologue, promotes cell divisions in the QC, but it suppresses columella stem cell differentiation, opposite to the action of BES1. PMID: 26136267
  4. BZR1 represses target genes by recruiting the Groucho/TUP1-like transcriptional corepressor TOPLESS. PMID: 24938363
  5. BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues PMID: 24381244
  6. BIL1/BZR1 increases plant resistance to insect feeding PMID: 25036120
  7. BZR1-interacting proteins have been identified as potential components of the brassinosteroid signaling pathway in Arabidopsis. PMID: 24019147
  8. Phosphatidic acid decreased BZR1 dephosphorylation to inhibit BZR1 activity and brassinosteroid signal response by regulating PP2A activity. PMID: 24121289
  9. BZR1 and AP2 probably affect Arabidopsis ovule number determination antagonistically PMID: 22914576
  10. BZR1 dissociates from the DWF4 (cytochrome P450 90B1) promoter in the presence of auxin, indicating DWF4 expression involves BZR1-mediated de-repression mechanisms. PMID: 21284753
  11. Data show that BZR1 not only controls the expression of many signaling components of other hormonal and light pathways but also coregulates common target genes with light-signaling transcription factors. PMID: 21074725
  12. results show that BZR1 coordinates brassinosteroid (BR) homeostasis and signaling by playing dual roles in regulating BR biosynthesis and downstream growth responses PMID: 15681342
  13. BZR1 functions as a nucleocytoplasmic shuttling protein and GSK3-like kinases induce the nuclear export of BZR1 by modulating BZR1 interaction with the 14-3-3 proteins. PMID: 17873094

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Subcellular Location
Protein Families
BZR/LAT61 family
Tissue Specificity
Accumulates in the growing region of the hypocotyl.
Database Links

KEGG: ath:AT1G75080

STRING: 3702.AT1G75080.1

UniGene: At.17945

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