C1galt1c1 Antibody

Datasheet

Code	CSB-PA003490XA01MO
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Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) C1galt1c1 Polyclonal antibody

Uniprot No.

Q9JMG2

Target Names

C1galt1c1

Alternative Names

C1galt1c1 antibody; CosmcC1GALT1-specific chaperone 1 antibody; Core 1 beta1,3-galactosyltransferase 2 antibody; C1Gal-T2 antibody; C1GalT2 antibody; Core 1 beta3-Gal-T2 antibody; mC1Gal-T2 antibody; Core 1 beta3-galactosyltransferase-specific molecular chaperone antibody

Raised in

Rabbit

Species Reactivity

Mus musculus (Mouse)

Immunogen

Recombinant Mus musculus (Mouse) C1galt1c1 protein

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).

Gene References into Functions

Cosmc is an inflammatory bowel disease risk factor and is implicated in regulating the spatial pattern of dysbiosis and sex bias in IBD. PMID: 27930307
These results demonstrated that core 1-derived O-glycan is required for Tim4-dependent normal efferocytosis and may contribute to the stable expression of the Tim4 glycoprotein. PMID: 29247646
Cosmc is an essential chaperone for correct protein O-glycosylation. PMID: 20439703
a somatic mutation in the chaperone gene Cosmc abolished function of a glycosyltransferase, disrupting O-glycan Core 1 synthesis & creating a tumor-specific glycopeptidic neo-epitope consisting of a monosaccharide and a specific wild-type protein sequence PMID: 17038624

Subcellular Location

Membrane; Single-pass type II membrane protein.

Protein Families

Glycosyltransferase 31 family, Beta3-Gal-T subfamily

Database Links

KEGG: mmu:59048

STRING: 10090.ENSMUSP00000059224

UniGene: Mm.441410

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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C1galt1c1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background