cdh2 Antibody

1. N-cadherin is involved in neuronal activity-dependent regulation of myelinating capacity of zebrafish individual oligodendrocytes in vivo. PMID: 27771903
2. N-cadherin-defective endodermal cells resembled ectodermal cells; expression of N-cadherin sufficient to induce internalization of ectodermal cells PMID: 28874564
3. In zebrafish, E-cadherin is expressed in lens epithelium, whereas N-cadherin is required for lens fiber growth PMID: 28196805
4. Newly synthesized N-cadherin molecules move from the lateral to the basal surface of cardiomyocytes during trabeculation. This localization requires Erbb2 signaling. PMID: 27339140
5. Throughout somitogenesis, Cadherin2 promotes extracellular matrix (ECM) assembly along tissue boundaries and inhibits ECM assembly in the tissue mesenchyme. PMID: 26853361
6. Cdon is required to localize N-cadherin to the cell membrane in migratory neural crest cells for directed migration. PMID: 26256768
7. shows that a dominant-negative nuclear localization mutant of Sox3 can cause ectopic expression of organizer genes via a mechanism that activates all of these earlier factors, resulting in later axis duplication including major bifurcations of the CNS. PMID: 20610482
8. Genetic suppression of N-cadherin function interferes with basal migration of retinal progenitors and subsequent regeneration of HuC/D(+) inner retinal neurons. PMID: 24154521
9. N-cadherin deficiency in Danio does not prevent the first tooth from starting to develop, but stops its development at the early cytodifferentiation stage and completely inhibits the development of the other first-generation teeth. PMID: 23396519
10. N-cadherin regulates motor axon growth and branching without severely affecting the mechanisms that control axonal target selection. PMID: 21452216
11. Slit-Robo signaling downregulates N-cadherin activity to allow apical retraction in newly generated retinal ganglion cells. PMID: 22219284
12. demonstration of a novel mechanism of cell adhesion, mediated by a complex of Protocadherin-19 (Pcdh19) and N-cadherin (Ncad) PMID: 22184198
13. zebrafish N-cadherin restricts cell proliferation in the dorsal region of the neural tube by regulating cell-cycle length. PMID: 21389116
14. Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation PMID: 21115806
15. the ratio of the number of cells undergoing neurogenic cell division to the total number of cells undergoing mitosis was decreased in retinas of n-cadherin knockout zebrafish. PMID: 20362667
16. Cadherin-2 plays a key role during zebrafish granule cell migration by continuously coordinating cell-cell contacts and cell polarity through the remodeling of adherens junctions. PMID: 19901980
17. Both Cdh2 and Cdh4 immunoreactivities were specifically up-regulated in regenerating retina and/or the optic pathway and both may be important for regeneration of injured retinal ganglion cell axons PMID: 12429186
18. cell adhesion mediated by N-cadherin is of major importance for retinal lamination and involved in maintenance of the lens epithelial sheet, but is not essential for the formation of photoreceptor ultrastructure or for synaptogenesis. PMID: 12619142
19. has several distinct and crucial functions during the establishment of retinal organization PMID: 12702661
20. Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning. PMID: 12812791
21. analyzed expression patterns of three zebrafish classical (type I) cadherins (cadherin-1, -2, and -4) in the embryonic zebrafish cranial ganglia and lateral line system PMID: 12972001
22. cadherin-2 is crucial for the normal development of the zebrafish pectoral fins PMID: 14648850
23. Dynamic and reciprocal waves of N-cadherin and M-cadherin expression within the myotome, which correlate precisely with cell migration, generate differential adhesive environments that drive slow-twitch muscle cell migration through the myotome. PMID: 14667409
24. cadherin-2 function is crucial for the normal formation of the zebrafish lateral line system and a subset of cranial ganglia PMID: 15108318
25. To investigate N-cadherin dynamics in developing axons, we used in vivo two-photon time-lapse microscopy of N-cadherin--green fluorescent protein (Ncad-GFP), which was expressed in Rohon-Beard neurons of the embryonic zebrafish spinal cord PMID: 15483121
26. myocardiocyte differentiation and physiological cardiovascular performance is impaired when cadherin2 function is disrupted. PMID: 16719917
27. We address the mechanisms underlying anterior neural tube morphogenesis in the zebrafish and the role of the cell adhesion molecule N-cadherin (N-cad) in this process. PMID: 16943271
28. N-cadherin is essential for morphogenesis of the mesodermal germ layer during gastrulation. PMID: 17826762
29. N-cadherin and other members of the classical cadherin subfamily function in parallel with the planar cell polarity pathway to shape the posterior axis during post-gastrulation stages PMID: 18045497
30. data reveal a novel role for cdh2 in the establishment of circuits by peripheral sensory neurons PMID: 19356698
31. N-cadherin stabilizes pre- to postsynaptic contacts early in synapse development, suggesting that regulated cleavage of the N-cadherin prodomain is a mechanism by which the kinetics of synaptogenesis are regulated. PMID: 19365814

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KEGG: dre:30291

STRING: 7955.ENSDARP00000003949

UniGene: Dr.75081