CAD4 Antibody

Code CSB-PA561996XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CAD4 Polyclonal antibody
Uniprot No.
Target Names
CAD4
Alternative Names
CAD4 antibody; CAD antibody; CAD-C antibody; CAD2 antibody; LCAD-C antibody; At3g19450 antibody; MLD14.19Cinnamyl alcohol dehydrogenase 4 antibody; AtCAD4 antibody; EC 1.1.1.195 antibody; Cinnamyl alcohol dehydrogenase C antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CAD4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in lignin biosynthesis in the floral stem. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
Gene References into Functions
  1. Data show that disruption of the genes encoding both cinnamyl alcohol dehydrogenases CADC (At3g19450) and CADD (At4g34230) results in the atypical incorporation of hydroxycinnamaldehydes into lignin. PMID: 26265762
  2. Repressing both the CAD and the CCR activities results in sterility and dwarfism. PMID: 20829305
  3. determined the crystal structures of AtCAD5 in the apo-form and as a binary complex with NADP+, respectively, and modeled that of AtCAD4. The substrate-binding pockets of both AtCAD5 and AtCAD4 were also examined. PMID: 16633561
Protein Families
Zinc-containing alcohol dehydrogenase family
Tissue Specificity
Expressed at the lateral root initiation sites, in the vascular tissues of the primary lateral root and the root caps. Expressed in the hypocotyl, cotyledon and leaf veins, apical meristem region, hydathodes, at the base of the trichomes and cauline leave
Database Links

KEGG: ath:AT3G19450

STRING: 3702.AT3G19450.1

UniGene: At.24340

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