cnx-1 Antibody

Code CSB-PA004485XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans cnx-1 Polyclonal antibody
Uniprot No.
Target Names
cnx-1
Alternative Names
cnx-1; ZK632.6; Calnexin; CeCNX-1
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans cnx-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death.
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle. Note=Perinuclear localization in excretory and germ cells. In intestinal cells, clustered signals around vacuoles with vesicles are detected.
Protein Families
Calreticulin family
Tissue Specificity
Expressed ubiquitously in every blastomere of the embryo up to the gastrulation stage. Expression becomes gradually restricted to the head and tail regions at the comma stage during embryogenesis. During postembryonic development, expressed prominently in
Database Links

KEGG: cel:CELE_ZK632.6

STRING: 6239.ZK632.6.1

UniGene: Cel.17175

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