tra-3 Antibody

Code CSB-PA637544XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans tra-3 Polyclonal antibody
Uniprot No.
Target Names
tra-3
Alternative Names
tra-3 antibody; clp-5 antibody; LLC1.1 antibody; Calpain-5 antibody; EC 3.4.22.- antibody; Sex-determining transformer protein 3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans tra-3 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for the correct female sexual development of the soma and germline in hermaphrodite animals, while being fully dispensable in males. Has calcium-dependent proteolytic activity and is involved in the cleavage of tra-2, for which it acts as a potentiator. Capable of calcium-dependent autolysis. Part of the necrosis cell death pathway. Required for necrosis of intestinal cells induced by B.thuringiensis endotoxin Cry6Aa.
Gene References into Functions
  1. A single nucleotide polymorphism in tra-3 leads to mutation F96L in the encoded calpain-like protease. This mutation attenuates the ability of CB4856 to grow larger at low temperature. PMID: 17335351
Protein Families
Peptidase C2 family
Tissue Specificity
Expressed in neuronal, but not in GABA-ergic neurons, intestinal, hypodermal and excretory tissues.
Database Links

KEGG: cel:CELE_LLC1.1

STRING: 6239.LLC1.1

UniGene: Cel.12258

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