CalpA Antibody

Datasheet

Code	CSB-PA604710XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) CalpA Polyclonal antibody

Uniprot No.

Q11002

Target Names

CalpA

Alternative Names

CalpA antibody; CG7563Calpain-A antibody; EC 3.4.22.- antibody; Calcium-activated neutral proteinase A antibody; CANP A) [Cleaved into: Calpain-A catalytic subunit] antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) CalpA protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Calcium-regulated non-lysosomal thiol-protease. Involved in the organization of the actin-related cytoskeleton during embryogenesis.

Gene References into Functions

Calpain A functions as part of a timing module in mitosis, at the interface between calcium signals and mitotic cycles of the Drosophila embryo. PMID: 27264536
Study demonstrates that CalpB but not the structurally related CalpA has an important modulator function during in vivo cell migration. PMID: 22827336
Data show that mutations that disrupted endogenous calpainA or calpainB activity in transgenic flies suppressed tau toxicity. PMID: 21858230

Subcellular Location

Cytoplasm.

Protein Families

Peptidase C2 family

Tissue Specificity

Localized to the anterior and posterior embryonic poles just after fertilization. Becomes distributed around the polar buds and just below the pole cells of the posterior pole during cleavage cycles. During these nuclear divisions anterior localization di

Database Links

KEGG: dme:Dmel_CG7563

STRING: 7227.FBpp0085714

UniGene: Dm.1726

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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CalpA Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background