SRV2 Antibody

Code CSB-PA325921XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SRV2 Polyclonal antibody
Uniprot No.
Target Names
SRV2
Alternative Names
SRV2 antibody; CAP1 antibody; YNL138W antibody; N1210 antibody; N1838 antibody; Adenylyl cyclase-associated protein antibody; CAP antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SRV2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.
Gene References into Functions
  1. in vivo roles of Srv2p in the regulation of the actin cytoskeleton during clathrin-mediated endocytosis. PMID: 26604224
  2. Srv2/cyclase-associated protein has a high-affinity interaction with ADP-actin monomers PMID: 15356265
Subcellular Location
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein Families
CAP family
Database Links

KEGG: sce:YNL138W

STRING: 4932.YNL138W

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