CarT Antibody

Code CSB-PA795110XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) CarT Polyclonal antibody
Uniprot No.
Target Names
CarT
Alternative Names
CarT antibody; CG9317Carcinine transporter antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) CarT protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Carcinine transporter which is required for recycling of the neurotransmitter histamine in photoreceptor neurons of the compound eye. Following histamine release from photoreceptors and its uptake by glia where it is converted to carcinine, required for the uptake of carcinine from glia into photoreceptor cells where it can be hydrolyzed by tan to form histamine and beta-alanine.
Gene References into Functions
  1. These results demonstrate that CarT transports the histamine metabolite carcinine into photoreceptor neurons, thus contributing an essential step to the histamine-carcinine cycle. PMID: 26653853
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, axon.
Protein Families
Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
Tissue Specificity
Expressed in photoreceptor cells.
Database Links

KEGG: dme:Dmel_CG9317

STRING: 7227.FBpp0080925

UniGene: Dm.4655

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