cbeA Antibody

Code CSB-PA302019XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) cbeA Polyclonal antibody
Uniprot No.
Target Names
cbeA
Alternative Names
cbeA antibody; yeeU antibody; b2004 antibody; JW1986Cytoskeleton bundling-enhancing antitoxin CbeA antibody; Antitoxin CbeA antibody; Antitoxin YeeU antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) cbeA protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of its cognate toxin CbtA (YeeV). It does not bind to the toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles; it is probably retained in the MreB and FtsZ filament bundles. The mechanism has been proposed to require intergenic DNA, in cis, between the cbeA (yeeU) and cbta (yeeV) genes. The intergenic region was not found to be necessary in another study. Also counteracts the morphological defects caused by overexpression of SulA and DicB on cell shape. Also counteracts the effect of non-cognate toxins YfkI and YpjF.
Subcellular Location
Cytoplasm.
Protein Families
CbeA/YafW/YfjZ antitoxin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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