CBF5 Antibody

Code CSB-PA888699XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CBF5 Polyclonal antibody
Uniprot No.
Target Names
CBF5
Alternative Names
CBF5 antibody; NAP57 antibody; At3g57150 antibody; F24I3.230H/ACA ribonucleoprotein complex subunit 4 antibody; EC 5.4.99.- antibody; CBF5 homolog antibody; Dyskerin antibody; Nopp-140-associated protein of 57 kDa homolog antibody; AtNAP57 antibody; Nucleolar protein NAP57 homolog antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CBF5 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.
Gene References into Functions
  1. [CBF5] Arabidopsis CBF5 interacts with NAF1 in planta. PMID: 17712600
  2. AtNAP57 is a conserved component of the telomerase RNP in multicellular organisms that is required for telomere maintenance. [AtNAP57] PMID: 18212040
  3. T66A NAP57 behaves as a dominant-negative inhibitor of telomerase. dyskerin is a conserved component of the telomerase RNP complex in higher eukaryotes that is required for maximal enzyme activity in vivo. PMID: 18212040
Subcellular Location
Nucleus, nucleolus.
Protein Families
Pseudouridine synthase TruB family
Database Links

KEGG: ath:AT3G57150

STRING: 3702.AT3G57150.1

UniGene: At.19647

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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