Agbl5 Antibody

Code CSB-PA001439XA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Agbl5 Polyclonal antibody
Uniprot No.
Target Names
Agbl5
Alternative Names
Agbl5 antibody; Ccp5 antibody; Cytosolic carboxypeptidase-like protein 5 antibody; EC 3.4.17.- antibody; ATP/GTP-binding protein-like 5 antibody
Raised in
Rabbit
Species Reactivity
Mus musculus (Mouse)
Immunogen
Recombinant Mus musculus (Mouse) Agbl5 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate. Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin. Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation.
Gene References into Functions
  1. Nna1 and CCP5 do not work coordinately in the same pathway in either the nervous system or spermatogenesis. PMID: 28128286
  2. CCP5 functions as a dual-functional deglutamylase cleaving both alpha- and gamma-linked glutamate from tubulin. PMID: 24022482
Subcellular Location
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody.
Protein Families
Peptidase M14 family
Tissue Specificity
Widely expressed. Highly expressed in testis, and moderately in pituitary, brain, eye and kidney.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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