ccpp-6 Antibody

Code CSB-PA138513XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ccpp-6 Polyclonal antibody
Uniprot No.
Target Names
ccpp-6
Alternative Names
ccpp-6 antibody; Nnac2 antibody; EEED8.6Cytosolic carboxypeptidase 6 antibody; EC 3.4.17.- antibody; ATP/GTP-binding protein-like 4 homolog antibody; CeAGBL4 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ccpp-6 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Metallocarboxypeptidase that catalyzes the removing of polyglutamate side chains that are present on the gamma-carboxyl group of glutamate residues of tubulin in sensory cilia. Probably via the deglutamylation of tubulin, promotes microtubule stability required for axon regrowth after injury. Also regulates microtubule dynamics in uterine muscle cells.
Gene References into Functions
  1. two evolutionarily divergent systems identify C. elegans CCPP-6 and its mammalian ortholog CCP5 as a tubulin deglutamylase PMID: 20519502
Subcellular Location
Cytoplasm.
Protein Families
Peptidase M14 family
Tissue Specificity
Expressed in labial and amphid neurons.
Database Links

KEGG: cel:CELE_EEED8.6

STRING: 6239.EEED8.6

UniGene: Cel.15545

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