CYCD3-1 Antibody

Code CSB-PA337197XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CYCD3-1 Polyclonal antibody
Uniprot No.
Target Names
CYCD3-1
Alternative Names
CYCD3-1 antibody; CYCD3 antibody; At4g34160 antibody; F28A23.80Cyclin-D3-1 antibody; Cyclin-delta-3 antibody; Cyclin-d3 antibody; G1/S-specific cyclin-D3-1 antibody; CycD3;1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CYCD3-1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in the control of the cell cycle at the G1/S (start) transition. Activates the G1/S phase transition in response to cytokinin hormone signal, but declines in response to sucrose starvation leading to G1 arrest. Involved in the induction of mitotic cell division. Plays an important role in the switch from cell proliferation to the final stages of differentiation during plant development. May not be involved in the activation of cell cycle in the root apical meristem (RAM) in the early phase of seed germination. Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division.
Gene References into Functions
  1. ANT does not regulate CYCD3;1 during petal growth. PMID: 25948704
  2. The direct target of both the bacterial cytokinins and plant putrescine was the expression of D3-type cyclins. PMID: 21459976
  3. CYCD3;1 dominantly drives the G1/S transition, and in sucrose-depleted cells the decline in CYCD3;1 levels leads to G1 arrest, which is overcome by ectopic CYCD3;1 expression. PMID: 16517759
  4. A combined action of ANT and CYCD3;1 promotes cell proliferation in leaf primordia and increases leaf size. PMID: 19508432
  5. Overlap between CYCD3;1 and E2Fa modulated genes substantiates their action in a common pathway with a key role in controlling the G1/S transition, with additional targets for CYCD3;1 in chromatin modification. PMID: 19662336

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Protein Families
Cyclin family, Cyclin D subfamily
Tissue Specificity
Highly expressed in roots and at lower levels in leaves and flowers. Expressed in vegetative shoot meristem and inflorescence.
Database Links

KEGG: ath:AT4G34160

STRING: 3702.AT4G34160.1

UniGene: At.22721

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