ccmH Antibody

Code CSB-PA273249XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) ccmH Polyclonal antibody
Uniprot No.
Target Names
ccmH
Alternative Names
ccmH antibody; yejP antibody; b2194 antibody; JW2182Cytochrome c-type biogenesis protein CcmH antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) ccmH protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.
Gene References into Functions
  1. mature CcmH is a periplasm-resident oxidoreductase anchored to the inner membrane by two transmembrane segments PMID: 22789558
  2. Data show that a variant System I for cytochrome c biogenesis in archaea and some bacteria has a novel CcmE and no CcmH. PMID: 16920107
  3. CcmH forms a tightly interlinked dimer by swapping its N-terminal helix between two monomers. PMID: 18625227
  4. The active-site cysteines of E. coli CcmH, as well as R42, S54, R63, were replaced with alanine and the replacement effect on cytochrome c production was tested. PMID: 18687332
Subcellular Location
Cell inner membrane; Multi-pass membrane protein.
Protein Families
CcmH/CycL/Ccl2/NrfF family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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