CycB Antibody

1. During meiotic prophase in Drosophila males, transcript for the core cell cycle protein Cyclin B1 (CycB) is expressed in spermatocytes, but the protein does not accumulate in spermatocytes until just before the meiotic divisions. PMID: 26443637
2. dFMRP and Caprin collaborate to control the cell cycle at the MBT by directly mediating the normal repression of maternal Cyclin B mRNA and the activation of zygotic fruhstart mRNA. PMID: 21068064
3. induced by myb in eye imaginal disc PMID: 11847115
4. Fzy/Cdc20 is responsible for catalyzing the first phase of cyclin B destruction that occurs on the mitotic spindle, whereas Fzr/Cdh1 is responsible for catalyzing the second phase of cyclin B destruction that occurs throughout the cell. PMID: 12082076
5. interphase extension after cycle 10 is probably controlled by both cyclin B limitation and the DNA-replication checkpoint PMID: 14681192
6. CycB is required for the division of germline stem cells and their precursors. PMID: 15723793
7. We identified cyclin B as a direct transcriptional target of Fos in Drosophila melanogaster, with Fos binding to a region upstream of the cyclin B gene in vivo and cyclin B mRNA being specifically reduced under Fos loss-of-function conditions. PMID: 16966382
8. A requirement of another Oskar-dependent factor in addition to Nanos is a mechanism for ensuring that Cyclin B regulation is strictly limited to the germline. PMID: 17360772
9. Hsp90 is required to localize CycB to the mitotic spindle. PMID: 17376965

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KEGG: dme:Dmel_CG3510

STRING: 7227.FBpp0071822

UniGene: Dm.7295