cye-1 Antibody

Code CSB-PA836630XA01CXX
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis briggsae cye-1 Polyclonal antibody
Uniprot No.
Target Names
cye-1
Alternative Names
cye-1 antibody; CBG12774 antibody; G1/S-specific cyclin-E antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis briggsae
Immunogen
Recombinant Caenorhabditis briggsae cye-1 protein
Immunogen Species
Caenorhabditis briggsae
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of seam cell daughter cells. Involved in the progression of cell division in the intestinal lineage in larvae, and in particular in endoreplication, a specific growth pathway in the intestinal epithelium, required for feeding and gut development in growing larvae. By controlling the activity of translational repressor gld-1, regulates the pool of germline stem cells and the size of the mitotic zone by preventing entry into meiosis. In addition, repression of expression by gld-1 prevents mitosis re-entry in meiotic germline cells.
Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein Families
Cyclin family, Cyclin E subfamily
Database Links

STRING: 6238.CBG12774

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