CDC48A Antibody

Code CSB-PA346189XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CDC48A Polyclonal antibody
Uniprot No.
Target Names
CDC48A
Alternative Names
CDC48A antibody; CDC48 antibody; At3g09840 antibody; F8A24.11Cell division control protein 48 homolog A antibody; AtCDC48a antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CDC48A protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion).
Gene References into Functions
  1. As an AAA ATPase, AtCDC48A likely serves to process the polyubiquitinated NLR substrate for final protein degradation by the 26S proteasome. [AtCDC48A] PMID: 27340941
  2. results indicate that the CDC48A(NPL4) complex actively removes sumoylated CenH3 from centromeres and disrupts centromeric heterochromatin to release bulk rRNA genes into the nucleolus for ribosome production. PMID: 25344531
  3. Arabidopsis (Arabidopsis thaliana) CDC48 is induced upon infection, interacts with MP in endoplasmic reticulum inclusions dependent on the MP N terminus, and promotes degradation of the protein. PMID: 23027663
  4. Employing fluorescence correlation spectroscopy, it was shown that CDC48A hexamers are part of larger complexes. PMID: 17693538
  5. critical for cytokinesis, cell expansion, and differentiation in plants PMID: 18660433

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Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, phragmoplast. Cell membrane; Peripheral membrane protein. Note=Primarily localized to the nucleus and, during cytokinesis, to the phragmoplast, a site where membrane vesicles are targeted in the deposition of new cell wall materials.
Protein Families
AAA ATPase family
Database Links

KEGG: ath:AT3G09840

STRING: 3702.AT3G09840.1

UniGene: At.21739

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