cdka-1 Antibody

Code CSB-PA633803XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans cdka-1 Polyclonal antibody
Uniprot No.
Target Names
cdka-1
Alternative Names
cdka-1 antibody; T23F11.3 antibody; Cyclin-dependent kinase 5 activator 1 antibody; p35 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans cdka-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Activator of the kinase cdk-5. In several motor neurons, promotes the polarized trafficking of synaptic vesicles and dense-core vesicles. In the ventral nerve cord, regulates the synaptic localization of the glutamate receptor, glr-1. In DA motor neurons, regulates axonal transport of synaptic vesicle precursors by inhibiting dynein-mediated retrograde transport. Regulates the polarized distribution of dense-core vesicles in DB motor neurons. May regulate these processes in association with cdk-5. May also play a role in GABAergic synaptic vesicle localization in the ventral nerve cord.
Subcellular Location
Cytoplasm. Cell projection, dendrite. Cell projection, axon.
Protein Families
Cyclin-dependent kinase 5 activator family
Tissue Specificity
Expressed in all classes of neurons in the ventral cord.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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