CDR1 Antibody

Datasheet

Code	CSB-PA955423XA01CZD
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) CDR1 Polyclonal antibody

Uniprot No.

Q5ANA3

Target Names

CDR1

Alternative Names

CDR1 antibody; CAALFM_C305220WA antibody; CaO19.13421 antibody; CaO19.6000Pleiotropic ABC efflux transporter of multiple drugs CDR1 antibody; Pleiotropic drug resistance protein CDR1 antibody

Raised in

Rabbit

Species Reactivity

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Immunogen

Recombinant Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) CDR1 protein

Immunogen Species

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Pleiotropic ABC efflux transporter that confers resistance to numerous chemicals including anisomycin, cycloheximide, fluconazole, miconazole, ketoconazole, itriconazole, nystatin, terbinafine, amorolfine, brefeldin A, amphotericin B, fluphenazine, as well as estrogen. Plays a role in farnesol-induced apoptotic process through glutathione efflux activity. Mediates in-to-out transloaction of membrane phospholipids including aminophospholipids and thus regulates asymmetric distribution of phosphatidylethanolamine. Exhibits nucleoside triphosphatase activity.

Gene References into Functions

The W1038S substitution leads to the loss of hydrophobic interactions and H-bond with residues of the neighbor NBD1, in the non-catalytic ATP-binding site area in Cdr1. PMID: 29410026
Study have examined the functional significance of the previously uncharacterized nucleotide binding domains (NBD) in Cdr1p. Results showed that these new motifs are functionally asymmetric in both NBDs i.e. the motif in NBD1 is critical for proper localisation or folding of Cdr1p and the motif in NBD2 is required for ATP hydrolysis. PMID: 27251950

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily

Database Links

KEGG: cal:CAALFM_C305220WA

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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