ced-1 Antibody

1. Phagocytosing muscle cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1. PMID: 30451835
2. The formation of such halos depends on the integrins PAT-2/PAT-3, UNC-112 and the GEF protein UIG-1, but not on the canonical ced-1/6/7 or ced-2/5/12 signaling modules. PMID: 24632947
3. CED-7 and TTR-52 may promote the efflux of PS from apoptotic cells through the generation of extracellular phosphatidylserine (PS) vesicles, which lead to exoplasmic leaflet (exPS) expression on phagocytes via TTR-52 and CED-1 to facilitate cell corpse clearance. PMID: 22727702
4. TTR-52 is therefore the first bridging molecule identified in C. elegans that mediates recognition of apoptotic cells by crosslinking the PtdSer 'eat me' signal with the phagocyte receptor CED-1. PMID: 20526330
5. study found that the intracellular protein sorting complex, retromer, was required for cell corpse clearance by mediating the recycling of CED-1; retromer probably acted through direct interaction with CED-1 in the cell corpse recognition pathway PMID: 20133524
6. Phagocytic receptors, which were thought to act specifically in initiating engulfment, also control phagosome maturation through the sequential activation of multiple effectors such as dynamin, PI(3)P, and Rab GTPases. PMID: 18351800
7. Unfolded protein response genes regulated by ced-1 are required for Caenorhabditis elegans innate immunity. PMID: 18606143
8. CED-1/SCARF1 and C03F11.3/CD36 are beta-glucan binding receptors and define an evolutionarily conserved pathway for the innate sensing of fungal pathogens. PMID: 19237602

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KEGG: cel:CELE_Y47H9C.4

STRING: 6239.Y47H9C.4a

UniGene: Cel.7093