ced-9 Antibody

Code CSB-PA331378XA01CXX
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis briggsae ced-9 Polyclonal antibody
Uniprot No.
Target Names
ced-9
Alternative Names
ced-9 antibody; CBG24606 antibody; Apoptosis regulator ced-9 antibody; Cell death protein 9 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis briggsae
Immunogen
Recombinant Caenorhabditis briggsae ced-9 protein
Immunogen Species
Caenorhabditis briggsae
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway.
Subcellular Location
Perikaryon. Cell junction, synapse. Endomembrane system; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
Protein Families
Bcl-2 family
Database Links

KEGG: cbr:CBG24606

STRING: 6238.CBG24606

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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