CSE4 Antibody

1. findings suggest that a stable Cse4 nucleosome is maintained by dynamic chaperone-in-residence Sc PMID: 24844245
2. The budding yeast centromere DNA element II wraps a stable Cse4 hemisome in either orientation in vivo. PMID: 24737863
3. Cse4 localization at a functional kinetochore does not require the recognition of a specific DNA sequence by the CBF3 complex; rather, its localization depends on stable interactions among kinetochore proteins. PMID: 25533342
4. Report show that Fpr3 regulates Cse4 proteolysis and the structural changes in CSe4 might be important for its interaction with Psh1. PMID: 24514906
5. phosphorylation is crucial in Psh1-assisted control of Cse4 levels and the Psh1-Cse4 association itself functions to prevent Cse4 misincorporation PMID: 25183013
6. Results indicate that Cse4 phosphorylation and its role in promoting faithful chromosome segregation. PMID: 23637466
7. N terminus of Cse4 is a target of ubiquitination and that this modification plays a major role in regulating its proteolytic degradation. PMID: 23525333
8. The budding yeast Saccharomyces cerevisiae centromere recruits two Cse4 (ScCENP-A) molecules, which are deposited during S phase and remain stably bound through late anaphase. The authors suggest that the centromere incorporates a Cse4-H4 tetramer. PMID: 23623551
9. Our results favor a H3-Cse4 heterotypic octamer at the budding yeast centromere PMID: 22693454
10. Methylation of CenH3 (Cse4) arginine 37 regulates kinetochore integrity and chromosome segregation PMID: 22615363
11. the occupancy of Cse4 at STB induces positive DNA supercoiling, with a linking difference (DeltaLk) contribution estimated between +1 and +2 units PMID: 21807992
12. These data suggest a role for Snf2 in the maintenance of point centromeres involving the removal of Cse4 from ectopic sites. PMID: 21505420
13. The association of Cse4 with the STB (zinc cluster DNA-binding proteins) is dependent on Scm3, the loading factor responsible for the incorporation of Cse4 into the nucleosome. PMID: 21173161
14. Data show that that the inner kinetochore complex (CBF3) is required for pericentric DNA looping at the Cse4p-containing nucleosome. PMID: 19656849
15. We demonstrate that Cse4 resides at the partitioning locus STB of the 2-microm plasmid. Cse4p-STB association is absolutely dependent on the plasmid partitioning proteins Rep1p and Rep2p and the integrity of the mitotic spindle. PMID: 16966420
16. Experimental evidence supports the model that the Cse4 nucleosome is an octamer, containing two copies each of Cse4, H2A, H2B, and H4. PMID: 19782029

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KEGG: sce:YKL049C

STRING: 4932.YKL049C