cgh-1 Antibody

Code CSB-PA850207XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans cgh-1 Polyclonal antibody
Uniprot No.
Target Names
cgh-1
Alternative Names
cgh-1 antibody; C07H6.5ATP-dependent RNA helicase cgh-1 antibody; EC 3.6.4.13 antibody; Conserved germline helicase 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans cgh-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes.
Gene References into Functions
  1. in developing oocytes CGH-1 particles accumulate specifically in response to meiotic development PMID: 15986473
  2. Regulation of physiological germ cell apoptosis is specifically influenced by certain functions of the CGH-1/CAR-1 RNA-proteinP complex. PMID: 16221731
  3. These results identify somatic and germ cell CGH-1 functions that are distinguished by the involvement of PATR-1, and reveal that during oogenesis, numerous translationally regulated mRNAs are specifically protected by a CGH-1-dependent mechanism. PMID: 18695045
Subcellular Location
Cytoplasm.
Protein Families
DEAD box helicase family, DDX6/DHH1 subfamily
Tissue Specificity
Expression is restricted to two germline precursors Z2 and Z3 in L1 stage hermaphrodites, and is detectable specifically in the gonad at low levels into the L3 stage. Expression is significantly higher during the early L4 stage. In adults, expression rema
Database Links

KEGG: cel:CELE_C07H6.5

STRING: 6239.C07H6.5.2

UniGene: Cel.17052

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