DES1 Antibody

Code CSB-PA843194XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DES1 Polyclonal antibody
Uniprot No.
Target Names
DES1
Alternative Names
DES1 antibody; At5g28030 antibody; F15F15.100Bifunctional cystathionine gamma-lyase/cysteine synthase antibody; EC 2.5.1.47 antibody; EC 4.4.1.1 antibody; Beta-substituted Ala synthase 4;3 antibody; ARAth-Bsas4;3 antibody; L-cysteine desulfhydrase 1 antibody; DES1 antibody; O-acetylserine antibody; thiol)-lyase antibody; OASTL antibody; Protein CS-LIKE antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana DES1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in maintaining Cys homeostasis through the desulfuration of L-cysteine. Modulates the generation of the signaling molecule sulfide in plant cytosol. Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein.
Gene References into Functions
  1. DES1 is required for abscisic acid (ABA)-dependent nitric oxide (NO) production PMID: 25266633
  2. Mutations of L-CYS DESULFHYDRASE 1 (DES1) impede H(2)S generation in the Arabidopsis cytosol and strongly affect plant metabolism. PMID: 23144183
  3. Mutation of DES1 leads to premature leaf senescence and significantly reduces the total cysteine desulfuration activity in leaves. PMID: 19955263
  4. Binding of the C-terminus of serine acetyltransferase by acetylserine sulfhydrylase contributes a large portion of the total binding energy during formation of the plant cysteine synthase complex. PMID: 17425333
Subcellular Location
Cytoplasm.
Protein Families
Cysteine synthase/cystathionine beta-synthase family
Database Links

KEGG: ath:AT5G28030

STRING: 3702.AT5G28030.1

UniGene: At.30769

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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