CLB5 Antibody

1. Results suggest that Clb5 has a unique ability to trigger premeiotic S phase and that the amino-terminal region of Clb5 contributes to its specificity and regulates the functions performed by the cyclin-Cdk complex. PMID: 22209902
2. The lack of Snf1 alpha-catalytic subunit down-regulates CLB5 expression. PMID: 20505334
3. In the presence of replication stress, the unstable Clb5 pool is stabilized, and such stabilization requires neither MBF transcriptional activity nor de novo protein synthesis. PMID: 20538605
4. The 'hydrophobic patch' (HP) of the Saccharomyces cerevisiae S-phase cyclin Clb5 facilitates its interaction with Orc6 (via its Cy or RXL motif), providing a mechanism that helps prevent rereplication from individual origins. PMID: 15611618
5. Activation of CLB5 during meiosis requires Clb5 activity, suggesting that CLB5 may be regulated by a positive feedback mechanism. PMID: 15654101
6. Absence of the B-type cyclin Clb5 leads to a delay of premeiotic S phase by separate mechanisms. PMID: 16254243
7. Clb5 is stable until mitosis PMID: 16508019
8. Phosphorylation of Fin1 from S phase to metaphase, by the cyclin-dependent kinase Clb5-Cdk1, inhibits Fin1 association with the spindle. In anaphase, when Clb5-Cdk1 is inactivated, Fin1 is dephosphorylated by the phosphatase Cdc14. PMID: 17173039
9. Clb5 proteolysis involves two different modes for targeting of Clb5 to the proteasome, an APC/C-dependent and an APC/C-independent mechanism. PMID: 17620341
10. The CLB5 promoter and have identified two middle sporulation elements (MSEs) that act as binding sites for Ndt80 and both MSE display differential effectiveness in their ability to function as cis-acting regulatory sequences in vivo. PMID: 18327887
11. The coincident destruction of securin, Clb5, and Dbf4 coordinates bulk chromosome segregation with segregation of ribosomal DNA. PMID: 18591250
12. The temporal program of chromosome replication: genomewide replication in clb5{Delta} Saccharomyces cerevisiae PMID: 18832352

Show More

Hide All

KEGG: sce:YPR120C

STRING: 4932.YPR120C