Hsp60C Antibody

Code CSB-PA893304XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Hsp60C Polyclonal antibody
Uniprot No.
Target Names
Hsp60C
Alternative Names
Hsp60C antibody; CG723560 kDa heat shock protein homolog 2 antibody; mitochondrial antibody; 60 kDa chaperonin antibody; CPN60 antibody; Heat shock protein 60 antibody; HSP-60 antibody; Hsp60 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Hsp60C protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Essential for proper development of trachea, spermatogonia and spermatocytes.
Gene References into Functions
  1. we characterized the Hsp60C gene (at 25F region), which shows high sequence homology with the other three Hsp60 genes of D. melanogaster.Hsp60C may also be involved in cation transport across the developing tracheal epithelial cells PMID: 16385159
  2. Results provide the first evidence for an essential role of Hsp60C in Drosophila oogenesis, especially in organization and maintenance of cytoskeletal and cell adhesion components. PMID: 18386820
Subcellular Location
Mitochondrion matrix.
Protein Families
Chaperonin (HSP60) family
Tissue Specificity
First detectable expression is seen in the posterior part of the dorsal tracheal trunk at stage 14-15, which marks the beginning of terminal tracheation. In the larval gut, expression in proventriculus is stronger than in midgut and hindgut. Malpighian tu
Database Links

KEGG: dme:Dmel_CG7235

STRING: 7227.FBpp0078742

UniGene: Dm.6406

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