chp Antibody

Code CSB-PA320929XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) chp Polyclonal antibody
Uniprot No.
Target Names
chp
Alternative Names
chp antibody; CHT antibody; CG1744Chaoptin antibody; Photoreceptor cell-specific membrane protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) chp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for photoreceptor cell morphogenesis. Mediates homophilic cellular adhesion.
Gene References into Functions
  1. Glycosylphosphatidylinositol -mannosyltransferase 2 is required for the GPI-mediated membrane attachment of several Glycosylphosphatidylinositol -anchored proteins, including the photoreceptor-specific cell adhesion molecule, chaoptin PMID: 22575127
  2. Spacemaker, a secreted protein expressed only in the eyes of insects with open rhabdom systems, acts together with Prominin and the cell adhesion molecule Chaoptin to choreograph the partitioning of rhabdomeres into an open system. PMID: 17036004
  3. N-linked glycosylation of Chp is essential for its stability and activity. PMID: 18588887
Subcellular Location
Cell membrane; Peripheral membrane protein; Extracellular side. Note=Extracellular surface of R-cell plasma membrane.
Protein Families
Chaoptin family
Tissue Specificity
Expressed in photoreceptor cells and their axons in the adult retina, the ocellus and larval photoreceptor organ.
Database Links

KEGG: dme:Dmel_CG1744

STRING: 7227.FBpp0303134

UniGene: Dm.21698

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