CKS1 Antibody

1. Mutation of the polo-like kinase Cdc5, which functions in both the mitotic entry and mitotic exit pathways, is lethal in combination with overexpressed CKS1 PMID: 27558135
2. Cks1 mediates recruitment of the 19S proteasome to the Paf1 complex, thereby promoting transcriptional elongation. PMID: 23825181
3. conservation of Cks hinge-region prolines reflects their functions in forming a Cdk binding interface and that ability of these prolines to control partitioning between monomer and dimer is a consequence of the beta-turn networks within the hinge. PMID: 21704044
4. These data suggest a model where binding of a complex consisting of Cks1, Cdk1, and the 19S proteasome to histone H4 leads to removal of nucleosomes via a nonproteolytic activity of the proteasome. PMID: 20855529
5. function in transcription for the cell cycle regulatory cyclin-dependent kinase Cdc28 (Cdk1) and its interacting protein, Cks1 PMID: 15629725
6. the first report of a direct physical interaction between ubiquitin and Cks1p, inferring a role for ubiquitin binding in the transcriptional function of Cks1p PMID: 17198374

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KEGG: sce:YBR135W

STRING: 4932.YBR135W