CLASP Antibody

Code CSB-PA557848XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CLASP Polyclonal antibody
Uniprot No.
Target Names
CLASP
Alternative Names
CLASP antibody; At2g20190/At2g20200 antibody; T2G17.1/F11A3.25CLIP-associated protein antibody; AtCLASP antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CLASP protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cortical microtubule plus-end tracking protein required for cell morphogenesis and cell division. Promotes the stabilization of dynamic microtubules during mitosis. Regulates microtubule-cortex attachment, thereby contributing to self-organization of cortical microtubules and subsequent cell shape.
Gene References into Functions
  1. These findings mechanistically link SABRE to CLASP-dependent microtubule organization, shedding new light on the function of SABRE-related proteins in eukaryotes. PMID: 24240534
  2. the microtubule-associated protein CLASP interacts with the retromer component sorting nexin 1 (SNX1) to mediate an association between endosomes and microtubules. PMID: 23477787
  3. Edge-induced microtubule depolymerization, is overcome by the CLASP proteins which accumulates at specific cell edges. PMID: 21847104
  4. Arabidopsis thaliana CLASP protein is a microtubule-associated protein that is involved in both cell division and cell expansion.[CLASP] PMID: 17873093
  5. findings show that AtCLASP is enriched at the plus ends of microtubules where it localizes behind the AtEB1b protein; AtCLASP is required for cell morphogenesis and cell division PMID: 18042620
  6. A novel mechanism where modulation of CLASP activity governs microtubule-cortex attachment, thereby contributing to self-organization of cortical microtubules, is identified. PMID: 18716054

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Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cell cortex.
Protein Families
CLASP family
Tissue Specificity
Expressed at a low level in all tissues, mostly in young developing tissues.
Database Links

KEGG: ath:AT2G20190

STRING: 3702.AT2G20190.1

UniGene: At.27510

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