clsB Antibody

Code CSB-PA699518XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) clsB Polyclonal antibody
Uniprot No.
Target Names
clsB
Alternative Names
clsB antibody; ybhO antibody; b0789 antibody; JW0772 antibody; Cardiolipin synthase B antibody; CL synthase antibody; EC 2.7.8.- antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) clsB protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate.
Gene References into Functions
  1. the expression of E. coli ClsB significantly increased PG and cardiolipin levels, with the growth deficiency of pgsA null strain also being complemented under such conditions. Identification of this alternative mechanism for PG synthesis not only expands our knowledge of bacterial anionic phospholipid biosynthesis PMID: 27760827
  2. Data indicate that the cardiolipin synthase DeltaclsABC mutant (clsA, clsB(ybhO) and clsC (ymdC))nlacks detectible cardiolipin (CL) regardless of growth phase or growth conditions. PMID: 22988102
Subcellular Location
Cell membrane; Peripheral membrane protein.
Protein Families
Phospholipase D family, Cardiolipin synthase subfamily, ClsB sub-subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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