CBL2 Antibody

Datasheet

Code	CSB-PA818513XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CBL2 Polyclonal antibody

Uniprot No.

Q8LAS7

Target Names

CBL2

Alternative Names

CBL2 antibody; SCABP1 antibody; At5g55990 antibody; MDA7.3Calcineurin B-like protein 2 antibody; SOS3-like calcium-binding protein 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana CBL2 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Binds four calcium ions per subunit. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Mediates the inactivation of the proton pump AHA2 by CIPK11. Probably involved in regulating signaling responses to abscisic acid.

Gene References into Functions

the calcium-independent activation of PKS24 by SCaBP1 is dependent on interaction of PKS24 with the C-terminal tail of SCaBP1. [SCaBP1] PMID: 24521877
CBL2-GFP exhibited dynamic patterns of subcellular localization, including several endomembrane compartments, the apical plasma membrane (PM), and cytoskeleton-like structures in pollen tubes. v PMID: 19686372

Subcellular Location

Vacuole membrane; Lipid-anchor. Note=The tonoplast localization is S-acylation dependent and is abolished by 2-bromopalmitate (2-BP) treatment.

Protein Families

Calcineurin regulatory subunit family

Tissue Specificity

Ubiquitous. Stronger expression in aerial parts. Expressed in guard cells, meristems and elongation zones of roots, mesophyll cells of leaves, cortex and pith of inflorescence stems and anthers and stamen filaments in flowers.

Database Links

KEGG: ath:AT5G55990

STRING: 3702.AT5G55990.1

UniGene: At.25275

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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CBL2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background