Cnot7 Antibody

1. This study identifies CNOT7 as an important regulator of RNA transport and translation in dendrites, as well as higher cognitive function. PMID: 28723570
2. study reports that a complex of BTG4 and CAF1 safeguards metaphase II arrest in mammalian eggs by deadenylating maternal mRNAs PMID: 27605379
3. Cnot7, a key component of deadenylation machinery, are also dormant maternal mRNAs that are recruited during oocyte maturation PMID: 26134871
4. Collectively, our data support a model of CNOT7, TOB1, CNOT1, and RNA-binding proteins collectively exerting post-transcriptional control on a metastasis suppressive transcriptional program to drive tumor cell metastasis PMID: 26807845
5. mCAF1-deficient mouse phenotype could be linked to a defect(s) in germ cells and/or to inadequate Sertoli cell function, leading to seminiferous tubule disorganization and finally to a total disappearance of germ cells PMID: 15199137
6. Gene deletion of Cnot7 caused abnormal sperm morphology in Sertoli cells from knockout mice. PMID: 15700538
7. Cnot7 is expressed in osteoblasts and is associated with mineralization. PMID: 16639713
8. Cnot7 is an endogenous suppressor of bone mass in adult mice and inhibits bone mass phenotype actions PMID: 17451368
9. Show that a let-7 miRNA-loaded RNA-induced silencing complex interacts with the poly(A)-binding protein and the CAF1 and CCR4 deadenylases for miRNA mediated deadenylation. PMID: 19716330

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KEGG: mmu:18983

STRING: 10090.ENSMUSP00000034012

UniGene: Mm.272551