sex-1 Antibody

Code CSB-PA336913XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans sex-1 Polyclonal antibody
Uniprot No.
Target Names
sex-1
Alternative Names
sex-1 antibody; cnr-14 antibody; nhr-24 antibody; nr1g1 antibody; F44A6.2Steroid hormone receptor family member cnr14 antibody; Nuclear receptor subfamily 1 group G member 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans sex-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transciptional regulator which is involved in the sex determination and X chromosome dosage compensation pathways. Directly binds to five 5'-A(G/C)(G/T)(T/G)C(A/G)-3' sites in the promoter of sex-determining factor xol-1 to negatively regulate its expression and promote hermaphrodite development. Together with fox-1 is involved in making the distinction between one and two X-chromosomes. Plays a role in the fox-1-mediated repression of the functionally active isoform (isoform b) of the sex-determining factor xol-1 gene to promote hermaphrodite development. Plays a role in the association of the dosage compensation complex proteins dpy-27 and sdc-3 with the hermaphrodite X chromosomes.
Subcellular Location
Nucleus.
Protein Families
Nuclear hormone receptor family, NR1 subfamily
Tissue Specificity
Most abundant in embryos.
Database Links

KEGG: cel:CELE_F44A6.2

STRING: 6239.F44A6.2.2

UniGene: Cel.17916

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