COBL Antibody

Code CSB-PA599234XA01DIL
Product Type Polyclonal Antibody
Uniprot No. E7F568
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) COBL protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Protein cordon-bleu cobl
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names cobl
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. Regulates neuron morphogenesis and increases branching of axons and dendrites (By similarity). Required for normal embryonic development, including normal development of laterality, normal body size and shape, as well as normal brain, heart and kidney development. Required for normal development of stereocilia and kinocilia in sensory hair cells of neuromasts in the posterior lateral line organ, and thus also for balance keeping and normal swimming behavior.
Subcellular Location Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, cytoskeleton, Cell projection, ruffle, Cytoplasm, Cytoplasm, cytosol
Database Links

STRING: 7955.ENSDARP00000108248

UniGene: Dr.83392

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