coil Antibody

Code CSB-PA548617XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) coil Polyclonal antibody
Uniprot No.
Target Names
coil
Alternative Names
coil antibody; CG8710Coilin antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) coil protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. Required for Cajal body formation.
Gene References into Functions
  1. Coiled, a member of the leukocyte antigen 6 (Ly6) family, is crucial for septate junction formation and blood-brain barrier integrity. PMID: 21613501
  2. coilin is required for normal Cajal body organization in Drosophila but is not essential for viability or production of functional gametes PMID: 19158395
Subcellular Location
Nucleus. Nucleus, nucleoplasm. Nucleus, Cajal body. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle.; [Isoform C]: Cytoplasm.
Protein Families
Coilin family
Tissue Specificity
In egg chambers expressed in the follicle cells, nurse cells and oocyte. Expressed in the larval brain, salivary glands, fat bodies and in the somatic hub cells at the tip of the testis. Expressed in the spermatogonia and spermatocytes, and in the adult e
Database Links

KEGG: dme:Dmel_CG8710

STRING: 7227.FBpp0100132

UniGene: Dm.520

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