corto Antibody

Code CSB-PA328210XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) corto Polyclonal antibody
Uniprot No.
Target Names
corto
Alternative Names
corto antibody; ccf antibody; CG2530Centrosomal and chromosomal factor antibody; CCF antibody; Chromocentrosomin antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) corto protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Essential protein required for proper condensation of mitotic chromosomes and progression through mitosis. Binds to specific polytene chromosome sites, many of which are shared with the posterior sex combs (Psc) protein. Involved in maintaining Abd-B repression outside its normal expression domain.
Gene References into Functions
  1. Elongin C and Corto bind the vein-promoting gene. PMID: 24204884
  2. Corto interacts with Polycomb-group proteins and the GAGA factor. PMID: 12771214
  3. Corto and DSP1 proteins co-localize at 91 sites on polytene chromosomes and co-immunoprecipitate in embryos. PMID: 16613610
  4. interaction between the Enhancer of Trithorax and Polycomb Corto and Cyclin G is involved in regulating the balance between cell proliferation and cell differentiation during abdominal epithelium development PMID: 18667003
Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome.
Database Links

KEGG: dme:Dmel_CG2530

STRING: 7227.FBpp0300441

UniGene: Dm.24160

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