Cyp2d26 Antibody

Code CSB-PA251407XA01RA
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Product Details

Full Product Name
Rabbit anti-Rattus norvegicus (Rat) Cyp2d26 Polyclonal antibody
Uniprot No.
Target Names
Cyp2d26
Alternative Names
Cyp2d26 antibody; Cyp2d-26 antibody; Cyp2d2Cytochrome P450 2D26 antibody; EC 1.14.14.1 antibody; CYPIID26 antibody; Cytochrome P450-CMF2 antibody; Cytochrome P450-DB2 antibody; Debrisoquine 4-hydroxylase antibody
Raised in
Rabbit
Species Reactivity
Rattus norvegicus (Rat)
Immunogen
Recombinant Rattus norvegicus (Rat) Cyp2d26 protein
Immunogen Species
Rattus norvegicus (Rat)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Gene References into Functions
  1. Panax notoginseng saponins had no significant effects on the activities of CYP2C9, CYP2D6, and CYP3A4, but it could induce the activity of CYP1A2 in rats in vivo. PMID: 22162298
  2. It shows the highest metabolic activities against enantiomers of carvedilol. PMID: 29415952
  3. amino acid residues at positions 43 and 45 are important for anchoring of the rat CYP2D proteins and their stabilities in the endoplasmic reticulum membrane PMID: 15474473
  4. The effects of the mutual substitution of amino acid residues at positions 216 and 219 between rat CYP2D1 and CYP2D2 on their microsomal contents and enzymatic functions are reported. PMID: 18191824
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein Families
Cytochrome P450 family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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