Cyp6a2 Antibody

Code CSB-PA789248XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Cyp6a2 Polyclonal antibody
Uniprot No.
Target Names
Cyp6a2
Alternative Names
Cyp6a2 antibody; CYT-P450-B1 antibody; CG9438 antibody; Cytochrome P450 6a2 antibody; EC 1.14.-.- antibody; CYPVIA2 antibody; Cytochrome P450-B1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Cyp6a2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Is involved in the breakdown of synthetic insecticides and may be involved in the metabolism of insect hormones.
Gene References into Functions
  1. Overexpression of functional Cyp6a2 was consistently associated with DDT resistance. Luciferase reporter gene assays revealed that an intact Nrf2/Maf binding site in the 5'-promoter core region enhanced the constitutive transcription of Cyp6a2. PMID: 24038867
  2. We find that Imidacloprid does not induce expression of the analyzed Cyp6g1 and Cyp6a2 genes. PMID: 23933061
  3. The active site of CYP6G1 is significantly smaller than that of CYP6A2 or the CYP3A4. PMID: 20583201
  4. point mutations in cytochrome P450 Cyp6a2 can have a prominent role in insecticide resistance PMID: 15030474
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein Families
Cytochrome P450 family
Database Links

KEGG: dme:Dmel_CG9438

STRING: 7227.FBpp0085466

UniGene: Dm.33529

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