CPH2 Antibody

Code CSB-PA987003XA01CZD
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Product Details

Full Product Name
Rabbit anti-Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) CPH2 Polyclonal antibody
Uniprot No.
Target Names
CPH2
Alternative Names
CPH2 antibody; CAALFM_C600280WA antibody; CaO19.1187 antibody; CaO19.8778Transcription factor CPH2 antibody; Candida pseudohyphal regulator 2 antibody
Raised in
Rabbit
Species Reactivity
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Immunogen
Recombinant Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) CPH2 protein
Immunogen Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor that positively controls filamentous growth, virulence, and invasiveness. Binds directly to the two SRE-1-like elements upstream of TEC1 and thus regulates positively expression of this important hyphal growth regulator. Functions independently of known signaling cascades involving EFG1. Regulates also gene expression during intestinal colonization but is not involved in host cell adhesion.
Gene References into Functions
  1. Cph2 binds to the promoters of HMS1 and other components of the regulatory circuit for GI tract colonization. PMID: 26342020
  2. Hms1 functions downstream of the cyclin Pcl1 and the cyclin-dependent kinase Pho85, both of which are required for temperature-dependent filamentation. PMID: 22365851
Subcellular Location
Nucleus.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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